Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alteative splicing and the use of alteative promoters results in multiple transcript variants.
Clonality
polyclonal
Host
Rabbit
Immunogen
NOS3
Immunogen Region
NOS3
Isotype
IgG
Molecular Weight
140kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000; IHC: 1:20 - 1:200
Synonyms
ECNOS, eNOS, nitric oxide synthase 3
Uniprot
P29474
Gene Id
4846
Research Area
Developmental biology, Signal Transduction, Metabolism, Cardiovascular, Stem Cells, Immunology, Neuroscience
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500 - 1:2000; IHC: 1:20 - 1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09945.pdf" target="_blank">Data Sheet</ a>