This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alteatively spliced transcripts encoding multiple isoforms have been observed for this gene.
Categories
Primary Antibodies
Clonality
polyclonal
Description
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
Host
Rabbit
Immunogen
mitogen-activated protein kinase kinase kinase kinase 3
Isotype
IgG
Molecular Weight
110 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
RAB8IPL1
Uniprot
Q8IVH8
Gene Id
8491
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)