The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
Clonality
polyclonal
Host
Rabbit
Immunogen
interleukin 2
Immunogen Region
interleukin 2
Isotype
IgG
Molecular Weight
22 kDa
Reactivity
Human
Recommended Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Synonyms
Aldesleukin, IL 2, IL2, interleukin 2, lymphokine, T cell growth factor, TCGF
Uniprot
P60568
Gene Id
3558
Research Area
Immunology, Cardiovascular, Signal Transduction
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09820.pdf" target="_blank">Data Sheet</ a>