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Home / Primary Antibodies / Polyclonal Antibodies

IGF1R antibody

SKU : BHA10804164

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Mfr.No.	FNab04170
Background	IGF1R, also named as CD221, is a receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). IGF1R binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity, the activated IGF1R is involved in cell growth and survival control. It is crucial for tumor transformation and survival of malignant cell. IGF1R is a heterotetrameric receptor, composed of two alpha subunits (130 kDa each) and two beta subunits (~98 kDa each) (PMID: 6279656). Both the alpha and beta subunits are synthesized from a single mRNA precursor. The precursor is then glycosylated, proteolytically cleaved, and crosslinked by cysteine bonds.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	insulin-like growth factor 1 receptor
Isotype	IgG
Molecular Weight	70 kDa,90-100 kDa, 130 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CD221, IGFIR, IGFR, JTK13

Antigen	IGF1R-Specific
Uniprot	P08069
Gene Id	3480
Research Area	Developmental biology, Signal Transduction, Metabolism, Immunology, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IP
Description	ELISA ; WB ; IP
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Manual	FNab04170.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804164	FNab04170	100ug	$300		Add to Cart

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