Phosphorylates diacylglycerol(DAG) to generate phosphatidic acid(PA). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization.
Host
Rabbit
Immunogen
diacylglycerol kinase, eta
Isotype
IgG
Molecular Weight
135 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
DAG kinase eta, DGK eta, DGKeta, DGKH, Diacylglycerol kinase eta, diacylglycerol kinase, eta, Diglyceride kinase eta, DKFZp761I1510
Uniprot
Q86XP1
Gene Id
160851
Research Area
Signal Transduction, Metabolism
Weight
135kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)