Guanine nucleotide exchange factor(GEF) activating RAB12. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Thereby, may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Guanine nucleotide exchange factor (GEF) activating RAB12. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Thereby, may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor.
Host
Rabbit
Immunogen
DENN/MADD domain containing 3
Isotype
IgG
Molecular Weight
136 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
DENN/MADD domain containing 3, DENND3, KIAA0870
Uniprot
A2RUS2
Gene Id
22898
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)