CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1.
Host
Rabbit
Immunogen
chromatin accessibility complex 1
Isotype
IgG
Molecular Weight
17 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
CHRAC15
Antigen
CHRAC1
Uniprot
Q9NRG0
Gene Id
54108
Research Area
Epigenetics
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)