Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
Clonality
polyclonal
Host
Rabbit
Immunogen
cystic fibrosis transmembrane conductance regulator(ATP-binding cassette sub-family C, member 7)
Immunogen Region
cystic fibrosis transmembrane conductance regulator(ATP-binding cassette sub-family C, member 7)
Isotype
IgG
Molecular Weight
168KDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000
Synonyms
ABC35, ABCC7, CF, CFTR, CFTR/MRP, MRP7, TNR CFTR
Uniprot
P13569
Gene Id
1080
Research Area
Metabolism
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500 - 1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10868.pdf" target="_blank">Data Sheet</ a>