CD20 is a 33-37 kDa transmembrane phosphoprotein. CD20 is a B-lymphocyte surface molecule that is widely expressed during B-cell ontogeny, from early pre-B-cell developmental stages until final differentiation into plasma cells. CD20 functions as calcium-permeable cation channel. It is involved in the regulation of B-cell activation and proliferation. CD20 serves as a useful target for antibody-mediated therapeutic depletion of B-cells.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
membrane-spanning 4-domains, subfamily A, member 1
Isotype
IgG
Molecular Weight
33 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
B lymphocyte antigen CD20, B1, Bp35, CD20, LEU 16, MS4A1, MS4A2, S7
Antigen
CD20
Uniprot
P11836
Research Area
Stem Cells, Immunology, Signal Transduction, Cancer
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)