Plays a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Plays a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
Host
Rabbit
Immunogen
caspase recruitment domain family, member 14
Isotype
IgG
Molecular Weight
113-120 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CARMA2
Antigen
CARD14
Uniprot
Q9BXL6
Gene Id
79092
Research Area
Immunology, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)