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Home / Primary Antibodies / Promotion

Aquaporin 4 antibody

SKU : BHA10800516

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Mfr.No.	FNab00521
Alternative Names	AQP4 ; AQP4 ; aquaporin4 ; NMO-IgG
Background	This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alteatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alteative in-frame translation termination codon.
Categories	Primary Antibodies
Cellular Localization	Membrane
Clonality	polyclonal
Description	Aquaporins are specialized water transport channels in plasma membranes of water-permeable tissues. Aquaporin-4 (AQP4) is the most abundant water channel in the human central nervous system and is important to fluid movements in brain. Aquaporin-4 exists as two isoforms, a long (M1) isoform with translation initiation at Met-1, and a shorter (M23) isoform with translation initiation at Met-23, with molecular weights around 35-37 kDa and 32-34 kDa, respectively.
Host	Rabbit
Immunogen	aquaporin 4
Isotype	IgG
Molecular Weight	35 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	membrane
Synonyms	AQP 4, AQP4, aquaporin 4, NMO-IgG

Uniprot	P55087
Gene Id	361
Research Area	Developmental biology, Neuroscience
Weight	35kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000
IP	1:200-1:1000
IHC	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab00521.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800516	FNab00521	100ug	$300		Add to Cart

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