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Home / Primary Antibodies / Polyclonal Antibodies

AMPK beta 2 antibody

SKU : BHA10800373

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Mfr.No.	FNab00378
Alternative Names	AMPKbeta2 ; AMPKsubunitbeta2 ; PRKAB2
Background	The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
Categories	Primary Antibodies
Cellular Localization	Cytosol, Ucleoplasm
Clonality	polyclonal
Host	Rabbit
Immunogen	protein kinase, AMP-activated, beta 2 non-catalytic subunit
Isotype	IgG
Molecular Weight	35 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	cytosol,nucleoplasm
Synonyms	AMPK beta 2, AMPK subunit beta 2, PRKAB2

Antigen	AMPK beta 2
Uniprot	O43741
Gene Id	5565
Research Area	Signal Transduction, Metabolism
Weight	30kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:500-1:5000

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab00378.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800373	FNab00378	100ug	$300		Add to Cart

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