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Home / Primary Antibodies / Promotion

ALDH2 antibody

SKU : BHA10800289

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Mfr.No.	FNab00291
Alternative Names	ALDHclass2 ; ALDHE2 ; ALDH2 ; ALDHI ; ALDM
Background	This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alteative splicing results in multiple transcript variants encoding distinct isoforms.
Categories	Primary Antibodies
Cellular Localization	Mitochondria
Clonality	polyclonal
Host	Rabbit
Immunogen	aldehyde dehydrogenase 2 family (mitochondrial)
Isotype	IgG
Molecular Weight	53 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Mitochondrion
Synonyms	ALDH class 2, ALDH E2, ALDH2, ALDHI, ALDM

Uniprot	P05091
Gene Id	217
Research Area	Metabolism
Weight	56kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IP

Description

ELISA ; WB ; IHC ; IP

Dilution

WB	1:500-1:5000
IHC	1:20-1:200
IF	1:50-1:500
IP	1:500-1:5000

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab00291.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800289	FNab00291	100ug	$300		Add to Cart

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