• Clonality :
• Monoclonal

• Description :
• This monoclonal antibody recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas.It it be usually employed in combination with other markers such as Synaptophysin,Chromogranin A, and Neurofilament.

• Formulation :
• 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

• Host :
• Mouse

• Immunogen Region :
• Amino acids 416-433 of human Neuron-specific Enolase were used as the immunogen for this NSE antibody.

• Isotype :
• IgG1,kappa

• Predicted Reactivity :
• Human

• Reactivity :
• Human

• Recombinant :
• No

• Subcellular Location :
• Cytoplasmic

• Antigen :
• NSE

• Uniprot :
• P09104

• Clone No :
• NSE-P2

• Concentration :
• 0.2 mg/ml

• Format :
• Purified

• Purification :
• Protein G affinity chromatography

• Storage :
• Store the NSE gamma antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

• Product Manual :
• <a href="http://www.nsjbio.com/tds-pdf/nse-gamma-antibody-nse-p2-v7731" target="_blank">Data Sheet</a>