• Clonality :
• Monoclonal

• Description :
• Neuregulin-1, also called Heregulin-1, is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

• Formulation :
• 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

• Host :
• Mouse

• Immunogen Region :
• A recombinant human partial protein (amino acids 21-242) was used as the immunogen for the NRG1 antibody.

• Isotype :
• IgG1,kappa

• Predicted Reactivity :
• Human

• Reactivity :
• Human

• Recombinant :
• No

• Subcellular Location :
• Cell surface, cytoplasmic

• Antigen :
• Neuregulin-1

• Uniprot :
• Q02297

• Clone No :
• HRGA1-1

• Concentration :
• 0.2 mg/ml

• Format :
• Purified

• Purification :
• Protein G affinity chromatography

• Storage :
• Store the NRG1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

• Product Manual :
• <a href="http://www.nsjbio.com/tds-pdf/nrg1-antibody-hrga1-1-v7634" target="_blank">Data Sheet</a>