• Clonality :
• Monoclonal

• Description :
• The protein encoded by the HAVCR2 gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. (RefSeq)

• Formulation :
• 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

• Host :
• Mouse

• Immunogen Region :
• A recombinant fragment of human TIM3 protein within amino acids 22-202 was used as the immunogen for the TIM3 antibody.

• Isotype :
• IgG2a,kappa

• Predicted Reactivity :
• Human

• Reactivity :
• Human

• Recombinant :
• No

• Subcellular Location :
• Cell surface, cytoplasmic

• Antigen :
• TIM-3

• Uniprot :
• Q8TDQ0

• Clone No :
• TMDP3-1

• Concentration :
• 0.2 mg/ml

• Format :
• Purified

• Purification :
• Protein G affinity chromatography

• Storage :
• Store the TIM3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

• Product Manual :
• <a href="http://www.nsjbio.com/tds-pdf/tim3-antibody-tmdp3-1-v7533" target="_blank">Data Sheet</a>