• Clonality :
• Monoclonal

• Description :
• Cadherins behave as both receptors and ligands for other molecules. During development, their behavior assists in properly positioning cells: they are responsible for the separation of the different tissue layers, and for cellular migration. In the very early stages of development, E-cadherin (epithelial cadherin) is most greatly expressed. The E-cadherin-catenin complex plays a key role in cellular adhesion; loss of this function has been associated with greater tumour metastasis. (Wiki)

• Formulation :
• 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

• Host :
• Rabbit

• Immunogen Region :
• Recombinant human protein was used as the immunogen for the recombinant E-Cadherin antibody.

• Isotype :
• IgG,kappa

• Predicted Reactivity :
• Human

• Reactivity :
• Human

• Recombinant :
• Yes

• Subcellular Location :
• Cytoplasmic, membranous

• Antigen :
• E-Cadherin

• Uniprot :
• P12830

• Clone No :
• ECD1-3R

• Concentration :
• 0.2 mg/ml

• Format :
• Purified

• Purification :
• Protein A affinity chromatography

• Storage :
• Store the recombinant E-Cadherin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

• Product Manual :
• <a href="http://www.nsjbio.com/tds-pdf/recombinant-e-cadherin-antibody-ecd1-3R-v3702" target="_blank">Data Sheet</a>