• Alternative Names :
• Teratocarcinoma-derived growth factor 1 (Cripto-1 growth factor) (CRGF) (Epidermal growth factor-like cripto protein CR1), TDGF1, CRIPTO

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Teratocarcinoma-derived growth factor 1 protein (35-188AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cell membrane, Lipid-anchor, GPI-anchor, Secreted

• Antigen :
• TDGF1

• Uniprot :
• P13385

• Database Links :
• 
  

  HGNC:11701

  OMIM:187395

  KEGG:hsa:6997

  STRING:9606.ENSP00000296145

  UniGene:Hs.385870

• Function :
• GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells

• Protein Families :
• EGF-CFC (Cripto-1/FRL1/Cryptic) family

• Research Area :
• Stem Cells

• Tissue Specificity :
• Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts. Expressed in breast and lung.

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :