TIA1 Antibody (CSB-PA023527DSR1HU)

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TIA1 Antibody (CSB-PA023527DSR1HU)

Alternative Names Nucleolysin TIA-1 isoform p40 (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1) (p40-TIA-1), TIA1
Categories Primary Antibodies
Clonality polyclonal

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suppilerCUSABIO TECHONOLOGY LLC
merchant skuCSB-PA023527DSR1HU
item price166.00000
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suppilerCOHESION BIOSCIENCES
merchant skuCSB-PA023527DSR1HU
item price168.78000
sale price168.78000
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Description

Description

Alternative Names :
Nucleolysin TIA-1 isoform p40 (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1) (p40-TIA-1), TIA1

Categories :
Primary Antibodies

Clonality :
polyclonal

Description :
Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.

Host :
Rabbit

Immunogen :
Recombinant Human Nucleolysin TIA-1 isoform p40 protein (1-193AA)

Involvement In Disease :
Welander distal myopathy (WDM)

Isotype :
IgG

Raised In :
Rabbit

Reactivity :
Human

Regulatory :
RUO

Relevance :
Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.

Species :
Homo Sapiens (Human)

Subcellular Location :
Cytoplasm, Stress granule, Nucleus

Target

Target

Antigen :
TIA1

Uniprot :
P31483

Database Links :
HGNC:11802
OMIM:603518
KEGG:hsa:7072
STRING:9606.ENSP00000401371
UniGene:Hs.413123

Function :
Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.

Research Area :
Cell Biology

Property

Property

Buffer :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form :
Liquid

Format :
Liquid

Purification :
Antigen Affinity Purified

Purity :
Antigen Affinity Purified

Storage :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Storage Buffer :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Applications

Applications

Application

Description

Dilution

Dilution: ELISA, WB, IHC, IP

Dilution: ELISA ; WB ; IHC ; IP, WB ; ELISA ; IHC ; IP

Dilution:

WB	1:1000-1:5000
IHC	1:20-1:200
IP	1:200-1:2000

Dilution: ELISA, WB, IHC, IP; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000

Protocols

Protocols

Datasheet :

ELISA Protocol :

Western Blotting(WB) Protocol :

Immunoprecipitation (IP) Protocol :

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