• Alternative Names :
• Myotubularin-related protein 14 (EC 3.1.3.-) (HCV NS5A-transactivated protein 4 splice variant A-binding protein 1) (NS5ATP4ABP1) (hJumpy), MTMR14, C3orf29

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Lipid phosphatase which efficiently dephosphorylates phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2; inactive toward PtdIns4P, PtdIns(3,4)P2, PtdIns(4,5)P2 and PtdIns(3,4,5)P3.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Myotubularin-related protein 14 protein (1-280AA)

• Involvement In Disease :
• Myopathy, centronuclear, 1 (CNM1)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Lipid phosphatase which efficiently dephosphorylates phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2; inactive toward PtdIns4P, PtdIns(3,4)P2, PtdIns(4,5)P2 and PtdIns(3,4,5)P3.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cytoplasm

• Uniprot :
• Q8NCE2

• Database Links :
• 
  

  HGNC:26190

  OMIM:160150

  KEGG:hsa:64419

  STRING:9606.ENSP00000296003

  UniGene:Hs.475382

• Function :
• Lipid phosphatase which efficiently dephosphorylates phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2; inactive toward PtdIns4P, PtdIns(3,4)P2, PtdIns(4,5)P2 and PtdIns(3,4,5)P3.

• Pathway :
• Autophagy Phosphatidylinositol signaling system

• Protein Families :
• Protein-tyrosine phosphatase family, Non-receptor class myotubularin subfamily

• Research Area :
• Microbiology

• Tissue Specificity :
• Expressed in various tissues, including heart, skeletal muscle, placenta, liver, lung, kidney and pancreas.

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :