• Alternative Names :
• Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein), SNAP25, SNAP

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Synaptosomal-associated protein 25 protein (1-206AA)

• Involvement In Disease :
• Myasthenic syndrome, congenital, 18 (CMS18)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cytoplasm, perinuclear region, Cell membrane, Lipid-anchor, Cell junction, synapse, synaptosome

• Antigen :
• SNAP25

• Uniprot :
• P60880

• Database Links :
• 
  

  HGNC:11132

  OMIM:600322

  KEGG:hsa:6616

  STRING:9606.ENSP00000254976

  UniGene:Hs.167317

• Function :
• t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.

• Pathway :
• Excitatory synapse pathway Secreted Extracellular Vesicles Synaptic vesicle cycle

• Protein Families :
• SNAP-25 family

• Research Area :
• Neuroscience

• Tissue Specificity :
• Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :