• Alternative Names :
• Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200), ASCC3, HELIC1

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3, enabling ALKHB3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions. Enhances NF-kappa-B, SRF and AP1 transactivation.1 Publication

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Activating signal cointegrator 1 complex subunit 3 protein (1-111AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3, enabling ALKHB3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions. Enhances NF-kappa-B, SRF and AP1 transactivation.1 Publication

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Nucleus

• Antigen :
• ASCC3

• Uniprot :
• Q8N3C0

• Gene Id :
• 10973

• Database Links :
• 
  

  HGNC:18697

  OMIM:614217

  KEGG:hsa:10973

  STRING:9606.ENSP00000358159

  UniGene:Hs.486031

• Function :
• 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions. Enhances NF-kappa-B, SRF and AP1 transactivation.

• Protein Families :
• Helicase family

• Research Area :
• Epigenetics and Nuclear Signaling

• Tissue Specificity :
• Ubiquitous.

• Weight :
• 83,675 Da

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :