• Alternative Names :
• Serpin B5 (Maspin) (Peptidase inhibitor 5) (PI-5), SERPINB5, PI5

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Serpin B5 protein (21-189AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Secreted, extracellular space

• Uniprot :
• P36952

• Database Links :
• 
  

  HGNC:8949

  OMIM:154790

  KEGG:hsa:5268

  STRING:9606.ENSP00000372221

  UniGene:Hs.55279

• Function :
• Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

• Pathway :
• p53 signaling pathway

• Protein Families :
• Serpin family, Ov-serpin subfamily

• Research Area :
• Tags & Cell Markers

• Tissue Specificity :
• Normal mammary epithelial cells.

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Western Blotting(WB) Protocol :

• Immunohistochemistry (IHC) Protocol :