• Alternative Names :
• Actin-related protein 3B (ARP3-beta) (Actin-like protein 3B) (Actin-related protein ARP4), ACTR3B, ARP11 ARP4

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Actin-related protein 3B protein (189-418AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cytoplasm, cytoskeleton, Cell projection

• Antigen :
• ACTR3B

• Uniprot :
• Q9P1U1

• Gene Id :
• 57180

• Database Links :
• 
  

  HGNC:17256

  KEGG:hsa:57180

  STRING:9606.ENSP00000256001

  UniGene:Hs.647117

• Function :
• Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors.

• Protein Families :
• Actin family, ARP3 subfamily

• Research Area :
• Signal Transduction

• Tissue Specificity :
• Detected in fetal brain. Detected throughout the adult brain, in neurons from gray matter, but not in white matter. Detected in liver, skeletal muscle and pancreas. Detected in lung adenocarcinoma cells with low metastatic potential, but not in lung adeno

• Weight :
• 48kDa

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity purified

• Purity :
• Antigen Affinity purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Western Blotting(WB) Protocol :

• Immunohistochemistry (IHC) Protocol :