• Alternative Names :
• Ubiquitin-like-conjugating enzyme ATG10 (EC 2.3.2.-) (Autophagy-related protein 10) (APG10-like), ATG10, APG10L

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Ubiquitin-like-conjugating enzyme ATG10 protein (1-220AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cytoplasm

• Antigen :
• ATG10

• Uniprot :
• Q9H0Y0

• Gene Id :
• 83734

• Database Links :
• 
  

  HGNC:20315

  OMIM:610800

  KEGG:hsa:83734

  STRING:9606.ENSP00000282185

  UniGene:Hs.713698

• Function :
• E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis.

• Pathway :
• Autophagy

• Protein Families :
• ATG10 family

• Research Area :
• Cell Biology

• Weight :
• 25279 MW

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :