• Alternative Names :
• DNA-binding protein RFX5 (Regulatory factor X 5), RFX5

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human DNA-binding protein RFX5 protein (367-616AA)

• Involvement In Disease :
• Bare lymphocyte syndrome 2 (BLS2)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Nucleus

• Uniprot :
• P48382

• Database Links :
• 
  

  HGNC:9986

  OMIM:209920

  KEGG:hsa:5993

  STRING:9606.ENSP00000290524

  UniGene:Hs.632472

• Function :
• Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters.

• Pathway :
• Antigen processing and presentation

• Protein Families :
• RFX family

• Research Area :
• Immunology

• Tissue Specificity :
• Ubiquitous.

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :