• Alternative Names :
• T-cell surface glycoprotein CD4 (T-cell surface antigen T4/Leu-3) (CD antigen CD4), CD4

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human T-cell surface glycoprotein CD4 protein (26-396AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cell membrane, Single-pass type I membrane protein

• Antigen :
• CD4

• Uniprot :
• P01730

• Database Links :
• 
  

  HGNC:1678

  OMIM:186940

  KEGG:hsa:920

  STRING:9606.ENSP00000011653

  UniGene:Hs.631659

• Function :
• Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule

• Pathway :
• Antigen processing and presentation Hematopoietic cell lineage T cell receptor signaling pathway Th1 and Th2 cell differentiation Th17 cell differentiation

• Research Area :
• Immunology

• Tissue Specificity :
• Highly expressed in T-helper cells. The presence of CD4 is a hallmark of T-helper cells which are specialized in the activation and growth of cytotoxic T-cells, regulation of B cells, or activation of phagocytes. CD4 is also present in other immune cells

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :