• Alternative Names :
• Nuclear receptor coactivator 4 (NCoA-4) (Androgen receptor coactivator 70 kDa protein) (70 kDa AR-activator) (70 kDa androgen receptor coactivator) (Androgen receptor-associated protein of 70 kDa) (Ret-activating protein ELE1), NCOA4, ARA70 ELE1 RFG

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Nuclear receptor coactivator 4 protein (1-280AA)

• Involvement In Disease :
• A chromosomal aberration involving NCOA4 is found in papillary thyroid carcinomas (PTCs). Inversion inv(10)(q11.2;q11.2) generates the RET/NCOA4 (PTC3) oncogene.

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma.

• Species :
• Homo Sapiens (Human)

• Antigen :
• NCOA4

• Uniprot :
• Q13772

• Gene Id :
• 8031

• Database Links :
• 
  

  HGNC:7671

  OMIM:601984

  KEGG:hsa:8031

  STRING:9606.ENSP00000395465

  UniGene:Hs.643658

• Function :
• Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma.

• Research Area :
• Signal Transduction

• Tissue Specificity :
• Widely expressed. Also detected in adipose tissues and in different cell lines. Isoform Beta is only expressed in testis.

• Weight :
• 73,649 Da

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :

• Immunofluorescence (IF) Protocol :