• Alternative Names :
• Anti-Muellerian hormone type-2 receptor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII), AMHR2, AMHR MISR2

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Anti-Muellerian hormone type-2 receptor protein (18-149AA)

• Involvement In Disease :
• Persistent Muellerian duct syndrome 2 (PMDS2)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human, Mouse

• Regulatory :
• RUO

• Relevance :
• On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Membrane, Single-pass type I membrane protein

• Antigen :
• AMHR2

• Uniprot :
• Q16671

• Gene Id :
• 269

• Database Links :
• 
  

  HGNC:465

  OMIM:261550

  KEGG:hsa:269

  STRING:9606.ENSP00000257863

  UniGene:Hs.659889

• Function :
• On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.

• Pathway :
• TGF-beta signaling pathway

• Protein Families :
• Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily

• Research Area :
• Signal Transduction

• Weight :
• 62750

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Western Blotting(WB) Protocol :

• Immunohistochemistry (IHC) Protocol :