• Alternative Names :
• Guanylate-binding protein 1 (EC 3.6.5.-) (GTP-binding protein 1) (GBP-1) (HuGBP-1) (Guanine nucleotide-binding protein 1) (Interferon-induced guanylate-binding protein 1), GBP1

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Interferon-induced guanylate-binding protein 1 protein (383-592AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cytoplasm, Golgi apparatus membrane, Lipid-anchor, Cytoplasmic side, Cell membrane, Secreted

• Uniprot :
• P32455

• Database Links :
• 
  

  HGNC:4182

  OMIM:600411

  KEGG:hsa:2633

  STRING:9606.ENSP00000359504

  UniGene:Hs.62661

• Function :
• Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.

• Pathway :
• NOD-like receptor signaling pathway

• Protein Families :
• TRAFAC class dynamin-like GTPase superfamily, GB1/RHD3-type GTPase family, GB1 subfamily

• Research Area :
• Immunology

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Western Blotting(WB) Protocol :

• Immunoprecipitation (IP) Protocol :