• Alternative Names :
• Adenylate kinase 2, mitochondrial (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) [Cleaved into: Adenylate kinase 2, mitochondrial, N-terminally processed], AK2, ADK2

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Adenylate kinase 2, mitochondrial protein (1-232AA)

• Involvement In Disease :
• Reticular dysgenesis (RDYS)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human, Mouse

• Regulatory :
• RUO

• Relevance :
• Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Mitochondrion intermembrane space

• Antigen :
• AK2

• Uniprot :
• P54819

• Gene Id :
• 204

• Database Links :
• 
  

  HGNC:362

  OMIM:103020

  KEGG:hsa:204

  STRING:9606.ENSP00000346921

  UniGene:Hs.470907

• Function :
• Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.

• Protein Families :
• Adenylate kinase family, AK2 subfamily

• Research Area :
• Cell Biology

• Tissue Specificity :
• Present in most tissues. Present at high level in heart, liver and kidney, and at low level in brain, skeletal muscle and skin. Present in thrombocytes but not in erythrocytes, which lack mitochondria. Present in all nucleated cell populations from blood,

• Weight :
• 26kDa

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Western Blotting(WB) Protocol :

• Immunohistochemistry (IHC) Protocol :