• Alternative Names :
• Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog) (Putative MAPK-activating protein PM09) (Putative NF-kappa-B-activating protein 107), CANT1, SHAPY

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP. Involved in proteoglycan synthesis.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Soluble calcium-activated nucleotidase 1 protein (102-401AA)

• Involvement In Disease :
• Desbuquois dysplasia 1 (DBQD1); Epiphyseal dysplasia, multiple, 7 (EDM7)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP. Involved in proteoglycan synthesis.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Endoplasmic reticulum membrane, Single-pass type II membrane protein, Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein, Cell membrane

• Antigen :
• CANT1

• Uniprot :
• Q8WVQ1

• Database Links :
• 
  

  HGNC:19721

  OMIM:251450

  KEGG:hsa:124583

  STRING:9606.ENSP00000307674

  UniGene:Hs.8859

• Function :
• Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP

• Protein Families :
• Apyrase family

• Research Area :
• Epigenetics and Nuclear Signaling

• Tissue Specificity :
• Widely expressed.

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :