• Alternative Names :
• Septin-7 (CDC10 protein homolog), SEPT7, CDC10

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Septin-7 protein (308-437AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human, Mouse

• Regulatory :
• RUO

• Relevance :
• Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cytoplasm, Chromosome, centromere, kinetochore, Cytoplasm, cytoskeleton, spindle, Cleavage furrow, Midbody, Cytoplasm, cytoskeleton, cilium axoneme, Cell projection, cilium, flagellum

• Antigen :
• SEPT7

• Uniprot :
• Q16181

• Database Links :
• 
  

  HGNC:1717

  OMIM:603151

  KEGG:hsa:989

  STRING:9606.ENSP00000381992

  UniGene:Hs.191346

• Function :
• Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation

• Protein Families :
• TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family

• Research Area :
• Cell Biology

• Tissue Specificity :
• Widely expressed.

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Western Blotting(WB) Protocol :

• Immunohistochemistry (IHC) Protocol :