EIF4A1 Antibody

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EIF4A1 Antibody

Alternative Names Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1), EIF4A1, DDX2A EIF4A
Categories Primary Antibodies
Clonality polyclonal

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suppilerCUSABIO TECHONOLOGY LLC
merchant skuCSB-PA007550ESR1HU
item price299.00000
sale price299.00000
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suppilerCOHESION BIOSCIENCES
merchant skuCSB-PA007550ESR1HU
item price168.78000
sale price168.78000
quantityUnlimited
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Description

Description

Alternative Names :
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1), EIF4A1, DDX2A EIF4A

Categories :
Primary Antibodies

Clonality :
polyclonal

Description :
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Host :
Rabbit

Immunogen :
Recombinant Human Eukaryotic initiation factor 4A-I protein (167-406AA)

Isotype :
IgG

Raised In :
Rabbit

Reactivity :
Human, Rat

Regulatory :
RUO

Relevance :
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Species :
Homo Sapiens (Human)

Target

Target

Antigen :
eIF4A1

Uniprot :
P60842

Database Links :
HGNC:3282
OMIM:602641
KEGG:hsa:1973
STRING:9606.ENSP00000293831
UniGene:Hs.129673

Function :
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Protein Families :
DEAD box helicase family, eIF4A subfamily

Research Area :
Epigenetics and Nuclear Signaling

Property

Property

Buffer :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form :
Liquid

Format :
Liquid

Purification :
Antigen Affinity Purified

Purity :
Antigen Affinity Purified

Storage :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Storage Buffer :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Applications

Applications

Application

Description

Dilution

Dilution: ELISA, WB, IHC

Dilution: ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution:

WB	1:500-5000
IHC	1:20-1:200

Dilution: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Protocols

Protocols

Datasheet :

ELISA Protocol :

Western Blotting(WB) Protocol :

Immunohistochemistry (IHC) Protocol :

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