• Alternative Names :
• MHC class I polypeptide-related sequence A (MIC-A), MICA, PERB11.1

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human MHC class I polypeptide-related sequence A protein (24-307AA)

• Involvement In Disease :
• Psoriasis 1 (PSORS1); Psoriatic arthritis (PSORAS)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cell membrane, Single-pass type I membrane protein, Cytoplasm

• Antigen :
• MICA

• Uniprot :
• Q29983

• Database Links :
• 
  

  HGNC:7090

  OMIM:177900

  KEGG:hsa:100507436

  UniGene:Hs.130838

• Function :
• Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.

• Pathway :
• Natural killer cell mediated cytotoxicity

• Protein Families :
• MHC class I family, MIC subfamily

• Research Area :
• Immunology

• Tissue Specificity :
• Widely expressed with the exception of the central nervous system where it is absent. Expressed predominantly in gastric epithelium and also in monocytes, keratinocytes, endothelial cells, fibroblasts and in the outer layer of Hassal's corpuscles within t

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :