• Alternative Names :
• Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M), IRAK3

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Interleukin-1 receptor-associated kinase 3 protein (367-596AA)

• Involvement In Disease :
• Asthma-related traits 5 (ASRT5)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.

• Species :
• Homo Sapiens (Human)

• Antigen :
• IRAK3

• Uniprot :
• Q9Y616

• Database Links :
• 
  

  HGNC:17020

  OMIM:604459

  KEGG:hsa:11213

  STRING:9606.ENSP00000261233

  UniGene:Hs.369265

• Function :
• Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.

• Pathway :
• Neurotrophin signaling pathway

• Protein Families :
• Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily

• Research Area :
• Immunology

• Tissue Specificity :
• Expressed predominantly in peripheral blood lymphocytes.

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :