• Alternative Names :
• Gastrotropin (GT) (Fatty acid-binding protein 6) (Ileal lipid-binding protein) (ILBP) (Intestinal 15 kDa protein) (I-15P) (Intestinal bile acid-binding protein) (I-BABP), FABP6, ILBP ILLBP

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Gastrotropin protein (1-128AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human, Mouse, Rat

• Regulatory :
• RUO

• Relevance :
• Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Isoform 1: Cytoplasm, Membrane, Peripheral membrane protein, Cytoplasmic side, SUBCELLULAR LOCATION: Isoform 2: Cytoplasm

• Antigen :
• FABP6

• Uniprot :
• P51161

• Database Links :
• 
  

  HGNC:3561

  OMIM:600422

  KEGG:hsa:2172

  STRING:9606.ENSP00000377549

  UniGene:Hs.519719

• Function :
• Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). In vitro binds to bile acids in the order

• Pathway :
• PPAR signaling pathway

• Protein Families :
• Calycin superfamily, Fatty-acid binding protein (FABP) family

• Research Area :
• Signal Transduction

• Tissue Specificity :
• Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is xpressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. Isoform 2 is expressed in c

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Western Blotting(WB) Protocol :

• Immunohistochemistry (IHC) Protocol :