• Alternative Names :
• Alpha-1-antichymotrypsin (ACT) (Cell growth-inhibiting gene 24/25 protein) (Serpin A3) [Cleaved into: Alpha-1-antichymotrypsin His-Pro-less], SERPINA3, AACT

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Alpha-1-antichymotrypsin protein (24-423AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Secreted

• Antigen :
• SERPINA3

• Uniprot :
• P01011

• Gene Id :
• 12

• Database Links :
• 
  

  HGNC:16

  OMIM:107280

  KEGG:hsa:12

  STRING:9606.ENSP00000376793

  UniGene:Hs.534293

• Function :
• Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.

• Protein Families :
• Serpin family

• Research Area :
• Neuroscience

• Tissue Specificity :
• Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains.

• Weight :
• 10,717 Da

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :