• Alternative Names :
• Interleukin-1 receptor-associated kinase-like 2 (IRAK-2), IRAK2

• Categories :
• Primary Antibodies, Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization., Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Interleukin-1 receptor-associated kinase-like 2 protein (1-270AA), Recombinant Human Interleukin-1 receptor-associated kinase-like 2 protein (1-270AA)

• Isotype :
• IgG

• Raised In :
• Rabbit, Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.

• Species :
• Homo Sapiens (Human)

• Antigen :
• IRAK2, IRAK2

• Uniprot :
• O43187, O43187

• Database Links :
• 
  

  HGNC:6113

  OMIM:603304

  KEGG:hsa:3656

  STRING:9606.ENSP00000256458

  UniGene:Hs.449207

  ,
  

  HGNC:6113

  OMIM:603304

  KEGG:hsa:3656

  STRING:9606.ENSP00000256458

  UniGene:Hs.449207

• Function :
• Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization., Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.

• Pathway :
• Neurotrophin signaling pathway, Neurotrophin signaling pathway

• Protein Families :
• Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily

• Research Area :
• Immunology, Immunology

• Tissue Specificity :
• Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes., Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified, Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze., Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :