• Alternative Names :
• Copper-transporting ATPase 2 (EC 3.6.3.54) (Copper pump 2) (Wilson disease-associated protein) [Cleaved into: WND/140 kDa], ATP7B, PWD WC1 WND

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Copper-transporting ATPase 2 protein (1166-1465AA), Recombinant Human Copper-transporting ATPase 2 protein (1166-1465AA)

• Involvement In Disease :
• Wilson disease (WD)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Golgi apparatus, trans-Golgi network membrane, Multi-pass membrane protein, Late endosome, Golgi apparatus, trans-Golgi network membrane, Multi-pass membrane protein, Late endosome

• Antigen :
• ATP7B

• Uniprot :
• P35670

• Gene Id :
• 540, 540

• Database Links :
• 
  

  HGNC:870

  OMIM:277900

  KEGG:hsa:540

  STRING:9606.ENSP00000242839

  UniGene:Hs.492280

  ,
  

  HGNC:870

  OMIM:277900

  KEGG:hsa:540

  STRING:9606.ENSP00000242839

  UniGene:Hs.492280

• Function :
• Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile., Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.

• Protein Families :
• Cation transport ATPase (P-type) (TC 3.A.3) family, Type IB subfamily, Cation transport ATPase (P-type) (TC 3.A.3) family, Type IB subfamily

• Research Area :
• Signal Transduction

• Tissue Specificity :
• Most abundant in liver and kidney and also found in brain. Isoform 2 is expressed in brain but not in liver. The cleaved form WND/140 kDa is found in liver cell lines and other tissues., Most abundant in liver and kidney and also found in brain. Isoform 2 is expressed in brain but not in liver. The cleaved form WND/140 kDa is found in liver cell lines and other tissues.

• Weight :
• 26,021 Da, 26,021 Da

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified, Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze., Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :

• Immunohistochemistry (IHC) Protocol :