• Alternative Names :
• Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5), MAP2K5, MEK5 MKK5 PRKMK5

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Dual specificity mitogen-activated protein kinase kinase 5 protein (1-190AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.

• Species :
• Homo Sapiens (Human)

• Antigen :
• MAP2K5

• Uniprot :
• Q13163

• Database Links :
• 
  

  HGNC:6845

  OMIM:602520

  KEGG:hsa:5607

  STRING:9606.ENSP00000178640

  UniGene:Hs.114198

• Function :
• Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.

• Pathway :
• MAPK signaling pathway Gap junction Neurotrophin signaling pathway

• Protein Families :
• Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily

• Research Area :
• Signal Transduction

• Tissue Specificity :
• Expressed in many adult tissues. Abundant in heart and skeletal muscle.

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :