• Alternative Names :
• X-linked retinitis pigmentosa GTPase regulator, RPGR, RP3 XLRP3

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes (By similarity). May be involved in microtubule organization and regulation of transport in primary cilia.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human X-linked retinitis pigmentosa GTPase regulator protein (1-180AA)

• Involvement In Disease :
• Retinitis pigmentosa 3 (RP3); Retinitis pigmentosa and sinorespiratory infections with or without deafness (RPDSI); Cone-rod dystrophy, X-linked 1 (CORDX1); Macular degeneration, X-linked, atrophic (MDXLA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes (By similarity). May be involved in microtubule organization and regulation of transport in primary cilia.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cytoplasm, cytoskeleton, flagellum axoneme, Golgi apparatus, SUBCELLULAR LOCATION: Isoform 6: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm, cytoskeleton, cilium basal body, Cytoplasm, cytoskeleton, cilium axoneme

• Uniprot :
• Q92834

• Database Links :
• 
  

  HGNC:10295

  OMIM:300029

  KEGG:hsa:6103

  STRING:9606.ENSP00000367766

  UniGene:Hs.61438

• Function :
• Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes (By similarity). May be involved in microtubule organization and regulation of transport in primary cilia.

• Research Area :
• Neuroscience

• Tissue Specificity :
• Heart, brain, placenta, lung, liver, muscle, kidney, retina, pancreas and fetal retinal pigment epithelium. Isoform 3 is found only in the retina. Colocalizes with RPGRIP1 in the outer segment of rod photoreceptors and cone outer segments.

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :