• Alternative Names :
• Gasdermin-B (Gasdermin-like protein), GSDMB, GSDML

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Gasdermin-B protein (63-310AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cytoplasm, Cytoplasm, cytosol, Cell membrane

• Uniprot :
• Q8TAX9

• Database Links :
• 
  

  HGNC:23690

  OMIM:611221

  KEGG:hsa:55876

  STRING:9606.ENSP00000353465

  UniGene:Hs.306777

• Function :
• The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores

• Protein Families :
• Gasdermin family

• Research Area :
• Cell Biology

• Tissue Specificity :
• In the gastrointestinal tract, expressed in proliferating cells, including in the basal cell layer of esophagus and in isthmus/neck of stomach.

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :

• Western Blotting(WB) Protocol :

• Immunohistochemistry (IHC) Protocol :