• Alternative Names :
• 39S ribosomal protein L41, mitochondrial (L41mt) (MRP-L41) (39S ribosomal protein L27 homolog) (Bcl-2-interacting mitochondrial ribosomal protein L41) (Cell proliferation-inducing gene 3 protein) (MRP-L27 homolog) (Mitochondrial large ribosomal subunit protein mL41), MRPL41, BMRP MRPL27 RPML27

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human 39S ribosomal protein L41, mitochondrial protein (14-137AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Mitochondrion

• Uniprot :
• Q8IXM3

• Database Links :
• 
  

  HGNC:14492

  OMIM:611846

  KEGG:hsa:64975

  STRING:9606.ENSP00000360498

  UniGene:Hs.44017

• Function :
• Component of the mitochondrial ribosome large subunit

• Protein Families :
• Mitochondrion-specific ribosomal protein mL41 family

• Research Area :
• Cell Biology

• Tissue Specificity :
• Present in kidney, liver, thymus and testis, and at lower level in brain and spleen (at protein level).

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :