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Human Renal Glomerular Endothelial Cells

SKU : BHC18000768

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AcceGen Biotech

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Mfr.No.	ABC-TC3783
Description	Renal glomerular endothelial cells (GEC) are a specialized microvascular cell type involved in the regulation of glomerular ultrafiltration. They form the inner part of the filtration barrier and are involved in pathophysiological processes in the glomerulum. They constitutIVely synthesize bio-actIVe molecules, to which this basal actIVIty can be chronically augmented by various inflammatory and thrombotic agents. GEC injury eXerts significant influences on the progression and repair process of glomerular disease. When the glomerular lesion is severe, angiogenesis is prevented due to endothelial cell injury, with subsequent sclerosis taking place in the impaired region. These glomerular endothelial cell injuries ineVItably affect mesangial and epithelial cells and presumably modify the progression of renal disease by reciprocally interacting with them. Because of difficulties associated with the culture, cloning and propagation, the biological properties of these cells remain largely unknown. HRGEC from AcceGen Research Laboratories are isolated from human kidneys. HRGEC are cryopreserved after purification and shipped with dry ice. Each VIal contains ;5×10^5 cells in 1 ml volume. HRGEC are characterized by immunofluorescent method with antibodies to vWF/Factor VIII and CD31 (P-CAM), and by the formation of microtublar structure in VItro. HRGEC are negatIVe for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HRGEC are guaranteed to eXpand beyond 15 population doublings at the conditions specified by AcceGen Research Laboratories.
Categories	Primary Cells
Species	Human
Applications	For research use only

Shipping	Dry Ice
Storage	Liquid Nitrogen
Quality Control	All cells test negatIVe for mycoplasma, bacteria, yeast, and fungi.

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SKU	Supplier No.	Your price	Quantity
BHC18000768	ABC-TC3783	-		Add to Quote

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