Human Primary Cardiomyocytes are isolated from human heart ventricles. Their specialized high-oxygen-content with a large number of mitochondria contributes to the major role of cardiac muscles in the hearts rhythmic pumping. Cardiomyocytes are regulated by a complex network of signals. Cardiomyocytes hypertrophy and apoptosis have been associated with the loss of contractile function during heart failure. They are ideal models for study of cytokines and cellular signaling mechanisms that lead to myocyte death, as well as for research on mechanical strain and cell-cell interaction.
Cell Type
Primary Cells
Disease
Normal
Gender
Female
Growth Properties
Adherent
Quantity
5x105 cells / 1.0 ml
Tissue
Heart
Morphology
Multipolar
Species
Human (H. sapiens)
Propagation
Use of PriCoatTMT25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) is required for cell adhesion to the culture vessels. Grow cells inECM-coated culture vessels unless otherwise specified in the Propagation Requirements below.The base medium for this cell line is Prigrow X series medium available at abm, Cat. No. TM4037. Carbon dioxide (CO2): 5%, Temperature: 37.0
Applications
For Research Use Only
Reviews of Human Primary Cardiac Microvascular Endothelial Cells