May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.
Categories
Primary Antibodies
Cellular Localization
endoplasmic reticulum, Membrane
Clonality
polyclonal
Description
May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.
Host
Rabbit
Immunogen
thioredoxin domain containing 11
Isotype
IgG
Molecular Weight
30 kDa
Reactivity
Human
Regulatory
RUO
Subcellular Location
Endoplasmic reticulum, Membrane
Synonyms
EF hand binding protein 1, EFP1, TXNDC11
Uniprot
Q6PKC3
Gene Id
51061
Research Area
Metabolism
Weight
30kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)