Mouse Anti-Human TRPC5 Monoclonal IgG2b

Mfr.No.	SMC-344, SMC-344D, SMC-344D-A390, SMC-344D-A488, SMC-344D-A594, SMC-344D-APC, SMC-344D-BI, SMC-344D-FITC, SMC-344D-HRP, SMC-344D-PCP, SMC-344D-RPE, SMC-344S
Immunogen Species	Human
Alternative Names	Htrp5 Antibody, Short transient receptor potential channel 5 Antibody, TRP5 Antibody
Categories	Antibodies
Cellular Localization	Membrane
Certificate Of Analysis	1 ug/ml of SMC-344 was sufficient for detection of TrpC5 in 20 ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Clonality	Monoclonal
Description	Mouse Anti-Human TrpC5 Monoclonal IgG2b
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Mouse
Gross Weight (kg)	1.4
Immunogen	Synthetic peptide amino acids 827-845 of human TrpC5 (also known as short transient receptor potential channel 5, and Htrp5), Homo Sapiens (Human)
Immunogen Region	Synthetic peptide amino acids 827-845 of human TrpC5 (also known as short transient receptor potential channel 5, and Htrp5)
Isotype	IgG2b
Launch Date	2010/09/09
Net Weight (g)	0.1
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Mouse, Rat, Human

Antigen	TRPC5
Swissprot	Q9UL62
Accession Number	NP_036603.1
Gene Id	7224
Target	TRPC5
Clone No	N67/15
Research Area	Ion Channels, Transient Receptor Potential (TRP) Channels, Cell Signaling, Neuroscience

Buffer	PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration	1 mg/ml
Dilutions	WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification	Protein G Purified
Scientific Background	Transient receptor potential cation channel, subfamily C, member 5, also known as TRPC5, is a subtype of the TRPC family of mammalian transient receptor potential ion channels. Homo-multimeric TRPC5 and hetero-multimeric TRPC5-TRPC1 channels are activated by extracellular reduced thioredoxin (1). This activation probably plays a role in rheumatoid arthritis. It has also been recently found to be involved in the action on anaesthetics such as chloroform, halothane and propofol (2).
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~110kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, IHC, IP, WB
Description	WB ; IHC ; IP ; AM
Dilution	WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

Reference	1. Xu S.Z., et al. (2008) Nature 451(7174): 69-72. 2. Bahnasi Y.M., et al. (2008) Br J. Pharamcol. 153(7): 1505-1512.

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11903241-1	SMC-344D	Unconjugated	100 ug	$337	Add to Cart
BHA11903241-2	SMC-344D-A390	ATTO 390	100 ug	$392	Add to Cart
BHA11903241-3	SMC-344D-A488	ATTO 488	100 ug	$391	Add to Cart
BHA11903241-4	SMC-344D-A594	ATTO 594	100 ug	$391	Add to Cart
BHA11903241-5	SMC-344D-APC	APC	100 ug	$390	Add to Cart
BHA11903241-6	SMC-344D-BI	Biotin	100 ug	$386	Add to Cart
BHA11903241-7	SMC-344D-FITC	FITC	100 ug	$381	Add to Cart
BHA11903241-8	SMC-344D-HRP	HRP	100 ug	$377	Add to Cart
BHA11903241-9	SMC-344D-PCP	PerCP	100 ug	$390	Add to Cart
BHA11903241-10	SMC-344D-RPE	RPE	100 ug	$388	Add to Cart
BHA11903241-11	SMC-344S	Unconjugated	12 ug	$45	Add to Cart

TRPC5 Antibody, Clone N67/15 (SMC-344)