Tropomyosin-3 binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Host
Rabbit
Immunogen Region
A portion of amino acids 245-276 from the human protein was used as the immunogen for the TPM3 antibody.
Isotype
Rabbit Ig
Species Reactivity
Human
Uniprot
P06753
Format
Antigen affinity purified
Purity
Antigen affinity
Storage
Aliquot the TPM3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.