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Home / Antibodies

STAT3 Monoclonal Antibody

SKU : BHA13715131

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Abbkine Scientific Co., Ltd.

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Mfr.No.	ABM0067
Alternative Names	STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor
Background	The protein encoded by STAT3 (signal transducer and activator of transcription 3) is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in STAT3 are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Clonality	Monoclonal
Description	Mouse Anti-STAT3 Monoclonal Antibody
Formulation	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen, Liquid solution
Host	Mouse
Immunogen	Recombinant Protein
Immunogen Region	Recombinant Protein
Isotype	Mouse IgG1
Molecular Weight	79, 86 KD
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Reactivity	Human, Mouse, Rat
Tag	STAT3
Note	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000-1:2000), IHC-P (1:100-1:200).

Accession Number	P40763
Gene Id	6774, 6774

Concentration	1 mg/ml, 1 mg/ml
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen, The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Storage Buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instructions	Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Applications	WB, IHC-P

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA13715131	ABM0067	100 uL	$229		Add to Cart

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